仙茅化学成分的研究

Chemical constituents from Curculigo orchioides

摘要:

为研究仙茅（Curculigo orchioides Gaertn）根茎中的化学成分，采用硅胶柱色谱、C18中压柱色谱、高压制备色谱对仙茅根茎甲醇提取物的正丁醇部位进行分离纯化，根据化合物的波谱数据鉴定其结构. 从中分离得到10个化合物，分别鉴定为2, 6-二甲氧基苯甲酸（1）、咖啡酸（2）、原儿茶酸（3）、orchioside B (4)、curculigoside C（5）、orchioside E（6）、丁香酸（7）、hemsleyanumoide（8）、丁香酸葡萄糖苷（9）、绿原酸 （10）. 其中，化合物6为1种新的酚苷类物质，命名为orchioside E，化合物2、8首次在仙茅中分离得到.

Abstract:

To study the chemical constituents in Curculigo orchioides Gaertn rhizomes, silica gel column chromatographies, C18 mediumpressure column chromatographies and high pressure preparative liquid chromatography system were used to isolate and purify the nbutanol portion of MeOH extract from the rhizomes of Curculigo orchioides. The structures were identified based on spectroscopic data. Ten compounds were isolated and identified as 2,6-dimethoxybenzoic acid (1), caffeic acid (2), protocatechuic acid (3), orchioside B (4), curculigoside C (5), orchioside E (6), syringic acid (7), hemsleyanumoide (8), glucosyringic acid (9), chlorogenic acid (10). Among them, compound 6 is a new phenolic glucoside named orchioside E, compound 2 and 8 are isolated from the Curculigo orchioides for the first time.