脱落酸ABA受体的功能以及翻译后修饰研究进展

The progress on the function and post-translational modification of ABA receptors

摘要:

脱落酸（Abscisic Acid，ABA）作为植物六大激素之一，在植物应对干旱、渗透等逆境胁迫条件下，维持植物体本身内环境的稳态中都起重要作用. ABA受体RCARs/PYR/PYLs结合ABA后抑制PP2C的活性来激活ABA信号转导途径. ABA受体作为ABA信号传递中的核心成员，其翻译后修饰对其功能有重要意义.本文主要总结了ABA受体的功能以及泛素化、硝基化和磷酸化修饰对其功能的精细调控的研究进展，并对该领域需解决的问题进行了展望.总结发现，ABA受体的不同修饰对其功能的影响不同，因此其翻译后修饰的研究可能对培育抗逆农作物品种具有理论指导意义.

Abstract:

Abscisic acid (ABA), as one of the six major phytohormones, plays an important role in maintaining the homeostasis of the internal environment under adverse stress conditions such as drought and osmotic stress. ABA receptors (RCARs/PYR/PYLs) bind to ABA and inhibit the activity of PP2C to activate the ABA signal transduction pathway. As a core member of ABA signaling, ABA receptors have post-translational modification (PTM) that is of great significance to their function in plant growth and development, and in responses to abiotic and biotic stresses. In this review, we summarize the recent works in RCARs’ functions and their fine regulation by PTM in plants and discuss new directions for future studies. In summary, different PTMs lead to variable functions of ABA receptors, thereby elucidation of PTMs would theoretically guide for cultivating stress-resistant crop varieties.