Separation and dentification of the chemical constituents of Toxicodendron vernicifluum leaves

Abstract:

In order to study the chemical constituents of Toxicodendron vernicifluum leaves, silica gel column chromatography, C18 medium pressure column chromatography and high pressure preparative chromatography were used to separate and purify the ethyl acetate portion of the ethanol extract from Toxicodendron vernicifluum leaves, and the structures of the compounds were identified by spectrum data. Eight compounds were isolated and identified as: gallic acid (1)，1,3,6-tri-O-galloyl-β-D-glucose (2)，1,2,4,6-tetra-O-galloyl-β-D-glucose(3)，astragalin (4), 1,2,3,4,6-penta-O-galloyl-β-D-glucose (5)，β- sitosterol (6)，shikimic acid (7)，engeletin(8). Among them, compounds 2, 3, 4, 7 and 8 were isolated from this plant for the first time, and compounds 1, 5 and 6 were isolated from the leaves of the plant for the first time.