Abstract:The properties of solutions of a class of chemotaxis system with logistic source are considered. By using prior estimates and the decay properties of Neumann heat semigroup, it is proved that there exists a unique global classical solution for the homogenous Neumann initial value problem in three-dimensional bounded domain with smooth boundary if the quadratic coefficient of the logistic source is sufficiently large.

Abstract:A characterization of flat ideals in the unit interval with the canonical fuzzy order is obtained with the help of the ordinal sum decomposition of continuous t-norms. This characterization will be useful in the study of topological and domain theoretic properties of fuzzy orders.

Abstract:Exact solutions of a class of space-time fractional mixed (1+1)-dimensional KdV equations with modified Riemann-Liouville fractional derivative are considered. Firstly, the nonlinear fractional partial differential equations are transformed into the nonlinear ordinary differential equations by means of the fractional complex transformation. Then, by applying the first integral method and Maple software, the exact solutions are obtained.

Abstract:We study the existence of some families of triple nested planar central configurations for the n-body problem with n=9, 12. For 9-body problem we show that there exist three families of triple nested triangular central configurations. For 12-body problem we show that there exist different families of triple nested regular polygonal central configurations in different cases.

Abstract:The boundedness and compactness of weighted iterated radial operators from weighted Bergman-Orlicz spaces to a class of bounded-type spaces are characterized by constructing some special functions.

Abstract:By using the fixed point theorem of Krasnosel'skii, we study the existence and multiplicity of symmetric positive solutions for a class of second-order three-point boundary value problem.

Abstract:In this paper, we examine a practical numerical method to solve a one-dimensional Riesz fractional diffusion equation with fractional boundary conditions. In order to propose an implicit finite difference method, we use the fractional centered derivative approach to approximate the Riesz fractional derivative and use the standard Grünwald-Letnikov fractional order operator to discrete the Riemann-Liouville fractional derivative in fractional boundary conditions. Then we discuss the existence and uniqueness of solution for the method. The stability, consistency and convergence of the method are also established. Finally, a numerical experiment is proposed to show the effectiveness of the method.

Abstract:Motivated by concepts in quantum mechanics and particle swarm optimization (PSO), quantumbehaved particle swarm optimization was proposed as a variant of PSO with better global search capability. This paper proposes a novel method for enhancing the global search capability of PSO and guiding its search with fractional calculus concepts. With the commonly used definitions of fractional differential known as GrünwaldLetnikov(GL), the authors introduce its discrete expression into the position update in QPSO to improve its convergence speed and accuracy. Some empirical studies on popular benchmark functions are performed in order to make a full evaluation on performance and comparison between standard QPSO and QPSO with different fractionalorder. The new algorithm, named fractionalorder Quantum particle swarm optimization, shows to perform well in finding optimal solutions with much higher convergence accuracy in many optimization problems.

Abstract:A method of stereo matching using each image fragments as a unit is proposed. Different from the conventional pixelbypixel stereo method， the authors use the edge information of the image to divide the reference image into small segments and perform stereo matching in units of small segments in the horizontal and vertical directions， and then use the disparity images to improve the accuracy of the matching. In each segment， the authors divide the matching cost into high cost and low cost and calculate the cost contribution of the two cost values to the entire segment in different calculation modes. This calculation method can accurately match the situation when the object is partially occluded.Next， the authors enlarge the loworder digit of the intensity for the two reference images and search for more accurate disparity values in all the fragments according to the enlarged reference images. Finally， the disparity map is filled and smoothed using the same color region median filter according to the original reference image.The results of the experiments show that this method has the characteristics of low computational complexity， fast speed， accurate matching， and clear edge disparity of the object. It achieved good performance with the Middlebury stereo benchmark.

Abstract:In order to solve the flow prediction problem of Internet of Things, a flow In order to solve the flow prediction problem of Internet of Things， a flow prediction model is proposed based on Bayesian and causal ridge regression.At first，the local characteristic of flow is deeply depicted considering the causal relationship between the fluctuation of the traffic flow and the change of the link;in addition, Schrodinger equation is used to optimize the recognition model.Then，the prediction model is built with Bayesian and causal ridge regression.Finally，the performance of this model and other methods is studied by simulation experiment.The results show that this model has a great advantage in average queue，blocking rate，delay rate and so on.

Abstract:The negative ideological are mostly qualitative analyzed at present, whichfailed to reveal the inherent law of ideological propagation. In order to solve the problem, the IHSRI (Ignorant HiddenSpread Removed Ignorant)model is proposedutilizing the method of virus propagation theory and mathematical modeling. Firstly, the authors analyze the conversion relationship between of Internet users under four states, that is, ignorant(I), hidden (H), spread (S) and removed (R).Then, the authorsestablish the corresponding mathematical propagation model. The equilibrium point of the model is calculated and the local stability of the model is analyzed and proved. The no negative equilibrium is locally asymptotically stable when the basic reproduction number R0 is less than or equal to 1; the negative equilibrium is locally asymptotically stable as the number R0 is greater than 1.Finally,the simulation result shows that the basic reproduction number R0 can be reduced from 5.71 to 2.67 when the transfer rate ε (transforming from H to R) increases from 0.04 to 0.2;R0 can be reduced from 5.71 to 1.07 when the proportionality coefficient αdecreases from 0.8 to 0.15.It can be seen that the value of R0 can be reduced by increasing ε and decreasing α, and the model can be approximated to the nonnegative equilibrium. The research shows that the IHSRI model can accurately describe the process of negative ideology propagation, which proved that this modelis reasonable and effective.

Abstract:The gain of array receiving signal is distorted due to the different gain of different frequency components in wideband signal；in order to solve the problem, an algorithm is proposed to improve constant beamwidth beamformer based on FIR. In this algorithm, the FIR filter array structure and microphone uniform line array features are utilized to determine the frequency range of constant beamwidth beamformer and obtain the array response with a constant beamwidth. In addition, the reference beam is designed to deal with the large fluctuation of the beamwidth between the adjacent cutoff frequencies, and the least square method is used to find the optimal weight. Finally, the optimal weight is normalized to gain a uniform gain. Computer simulation and experimental results verify the effectiveness of the algorithm.

Abstract:In view of the threshold sensitive problem of VFH series algorithms，a new adaptive threshold improvement strategy is proposed. First the initial threshold and the threshold range is determined by the hardware，motion characteristics of the robot and the target environment. Then, a threshold evaluation function is used to comprehensively evaluate each threshold and accessible direction in the optional range，so that the robot can get the threshold suitable for the current situation in real time. Finally，the algorithm is realized in ROS，and several comparative experiments are conducted using the EAI mobile robot platform. The experimental results show that when the improved policy with adaptive threshold is applied，the robot can avoid local dead zone and successfully reach the target position in complex environment, especially when the target is surrounded with obstacles.

Abstract:In data mining, the discretization of data can improve the efficiency of data mining effectively. In this paper, we propose a data preprocessing algorithm (AOA) to obtain the optimal discretization using parallel comparison. For different data sets, we first perform the feature detection of the data set to obtain the distribution characteristics of the data set. Then the outliers of the data set are detected according to the distribution characteristics. IN addition, the discretization results are obtained by comparing the minimum Euclidean distance of the entropy, the variance index and the stability parameter of the different discretization methods. In simulation experiment, we compare the AOA with four typical data discretization methods in different databases by running the association rule mining algorithm on the discretization data obtained using AOA and other four methods, respectively. The results show that, under different minimum support thresholds, the number of association rules extracted from the discretization data obtained using AOA is the least, indicating higher efficiency of AOA.

Abstract:The strength and equation of state of niobium (Nb) have be investigated using quasi-hydrostatic x-ray diffraction with helium as pressure medium up to 41 GPa, as well as radial x-ray diffraction up to 70 GPa in a 2-fold paranomic diamond anvil cell (DAC) at ambient temperature. The quasi-hydrostatic x-ray diffraction data (XRD) yields a bulk modulus and its pressure derivative as K0=166(2) GPa with K0'=3.2(2). The ratio of t/G is found to remain constant above ~6 GPa, indicating that the niobium started to experience yield with plastic deformation at this pressure. Combined with independent constraints on the high-pressure shear modulus, we found that niobium sample could support a differential stress of ~1.26 GPa when it started to yield with plastic deformation at ~6 GPa under uniaxial compression. The differential stress in niobium ranges from 0.03 GPa to 1.26 GPa with pressure increasing from 2 GPa to 6 GPa and can be described as t=-0.557(94)+0.306(21)P, where P is the pressure in GPa. The second increasing of t values occurs after ~30 GPa, suggesting that strengthen of Nb with a strength of ~1.67 GPa. A maximum differential stress, as high as ~3.96 GPa can be supported by niobium at the high pressure of ~70 GPa.

Abstract:The stabilities and magnetic properties of ZnSe clusters doped with one and two V atoms have been studied in term of a first-principles method. Substitutional, exohedral, and endohedral doping modes are considered. The exohedral isomers are found to be most favorable for both monodoped and bidoped clusters. Most importantly, the total magnetic moments of monodoped clusters are related to dopping pisotion, which have potential utility in new material with tunable magnetic properties.

Abstract:Using the pseudo-potential plane-wave based on the density functional theory (DFT), the band structure, electron density of states and optical properties of intrinsic ZnS, N-, Cu -N and Cu-2 N co-doped ZnS were calculated. The calculation results show that the co-doped systems can reduce the band gap and enhance its Photocatalytic properties. According to the Analysis of the density of states, the co-doped system of Cu-2N make the state density become more diffuse, more state density through the Fermi level, which obviously led to formation of p-type ZnS. At some time, Cu/N co-doping greatly increase the absorption of visible region owing to the lower transition energy of co-doped systems .

Abstract:In this study, the Geant4 toolkit is used to simulate a Compton suppression system based upon a HPGe primary detector for radioactive environment such as nuclear plant accident. LaBr3(Ce) crystal is selected for the anti-coincidence secondary detector. Simulations for the detector system are performed to gain the optimal sizes for 500 keV – 1500 keV γ rays. Simulation results show that the Peak Compton Suppression Factors (Peak CSFs) increase significantly with the thickness increase of the body LaBr3(Ce) crystal from 10 to 60 mm, the Peak CSFs do not increase obviously after the thickness of the body LaBr3(Ce) crystal reaches 60-70 mm; Moreover, adding a LaBr3(Ce) crystal to the back of the HPGe detector can also improve the Peak CSFs, but adding a LaBr3(Ce) crystal to the front of the HPGe detector has little effect on improving the Peak CSFs. Finally, we simulate a variety of sources in our Compton suppression system under the optimal conditions: for Cs-137 and K-40 that decay via a single γ emission Compton suppression effects are good; for I-131 and Cs-134 that decay in cascade some improvements are still obtained.

Abstract:The electronic and magnetic properties of ZnO nanowires doped with one and two Fe atoms are comparatively studied in terms of the first-principles calculation. The formation energies of doped nanowires are smaller than those of the pristine ones, indicating that the doping process is an exothermic reaction. The result shows that Fe atom prefers to the surface position. The magnetic moments are mainly contributed by the Fe-3d orbital. Due to the hybridization interaction, a small magnetic moment is also induced in nearest neighboring O atoms. The magnetic moments of the Fe and O atoms have the same direction, indicating ferromagnetic coupling between them. Surface doped nanowire is semiconductor, while middle doped nanowire is half-metalic, which have important applications in spintronics.

Abstract:Using the first-principles method based on density functional theory, we have studied the structural properties of GaN with wurtzite, zinc-blende and rocksalt structures and the phase transition of GaN under high pressure. According to the isoenthalpy principle, the phase transition pressure from zinc-blende structure to rocksalt structure of GaN is about 41.9GPa, which is consistent with the experimental results and other theoretical results. Employing the quasi-harmonic Debye mode, we have calculated the relationships between the thermal expansion coefficient and the pressure of GaN with zinc-blende structure and rocksalt structure at different temperatures. The relationships between the volume and pressure at different temperatures, and those between the heat capacity and temperature under different pressures are also obtained.

Abstract:By using the first principles method based on the density functional theory, the volume, elastic constants, elastic modulus and the phonon dispersion curve as well as the generalized stacking fault energies of bcc metals W and Mo have been investigated at the pressure from 0GPa to 100GPa, and the mechanical stability, the brittle-ductile properties and the shear deformation of the two materials have also been studied at the same pressure. Firstly, by calculating the elastic constants of the two materials at the pressure from 0-100GPa, it is found the elastic constants of each material satisfy the conditions of mechanical stability, moreover, the frequency of the phonon dispersion curves at 100GPa is positive and there is no imaginary frequency, therefore, both the structures of the W and Mo are mechanical stable at the pressure from 0-100GPa. Besides, through analyzing the ratio of the bulk modulus and the shear modulus, it is found that the high pressure can make the ductility of the W and Mo stronger, and the ductility of Mo is better than that of W. Finally, the generalized stacking fault energies, shear modulus G111 along the <111> direction and the anisotropy ratio A of the two materials are all investigated and it is found that, both the generalized stacking fault energies and G111 as well as A all increase when the pressure becomes higher, and the value of A is very close to 1 at 100GPa, all these indicate that the high pressure makes the shear deformation become more difficult and the weakens the anisotropy of W and Mo.

Abstract:Three-dimensional quantitative structure-activity relationship analysis of 37 6-azasteroids inhibitors was carried out by Topomer CoMFA. The new model’s cross validation and correlation coefficient were q2=0.774 and r2=0.965, respectively. The results show that the model has good prediction ability and reliability. Virtual screening based on Topomer search of ligand,virtual screening based on molecular docking of receptor and molecular activity prediction of 3D-QSAR model were applied to the new inhibitor grading screening. Finally, four new inhibitor compounds with high activity were obtained. The Surflex-dock results of new inhibitors showed that the interaction pattern between 6-azosterol inhibitors and 5α-reductaseⅡ target is mainly hydrogen bonding. The results of MTT assay showed that the new inhibitor could significantly inhibit the proliferation of BPH-1 cells and the degree of inhibition is concentration dependent. Molecular docking mechanism interpretation and prostatic growth inhibition assay in cytological experiments are mutually validated. It is proved that this virtual screening method can provide effective candidate compounds for the treatment of benign prostatic hyperplasia.

Abstract:SeMet/CS Nanocomposite microspheres were prepared using SeMet as a core material and chitosan(CS) as a wall material using emulsion crosslinking. The work in this paper focused on the indicators of microspheric form, drug-loading rate, entrapment efficiency and slow-release property using the single-factor and orthogonal test to optimize the preparation technology. During the processes, a scanning electron microscope, a Fourier infrared spectrometer, a thermal analyzer and double-channel atomic fluorescence were applied for detection, analysis and characterization. Furthermore, in vitro tests, such as for the selenium-releasing property and anticancer activity, were studied for the prepared selenium microsphere. The data indicated that the SeMet/CS microsphere prepared under the optimum conditions of 0.1% dosage and 2% dosage of crosslinking agent were crosslinked at 50℃ for 10 min. The obtained SeMet/CS microspheres exhibited superior features, with an Excellent morphology and an embedding ratio and drug loading of 31.94% and 0.59%, respectively. They displayed excellent sustained-release capability in an SBF model. Regarding anticancer activity, they showed a significant inhibitory effect on MCF-7 human breast cancer cells, and there was a positively correlated between the inhibition rate and the content of selenium in the sustained-release liquid. The SeMet/CS microsphere can effectively avoid a burst effect for selenium, allowing a controlled selenium dose. Thus, it can be used in selenide or selenium supplements for further application in medical, food and fine chemical industries.

Abstract:Graphitic carbon nitride (g-C3N4) possesses good physical and chemical stability, suitable band structure and efficient visible light response, which has attracted numerous attention for photocatalytic applications. As heterogeneous catalyst, high surface area can provide abundant reaction sites, increase contact between reactants and catalyst, and enhance mass transfer, which are beneficial for catalytic efficiency enhancement. This review focuses on the preparation and photocatalytic applications of g-C3N4 with high surface area. Two major strategies are reviewed, which are template method for porous g-C3N4 preparation and exfoliation for thin-layer g-C3N4 nanosheet preparation. In addition, the photocatalytic applications of g-C3N4 are introduced. Finally, the prospective of g-C3N4 is described.

Abstract:In this paper, the LiFePO4 thin films based on three-dimensional (3-D) TiO2 nanotubes were prepared by radio frequency (RF) magnetron sputtering method. The results show that the contact area between LiFePO4 film and the electrolyte and the utilization efficiency of the cathode material were increased with the help of this 3-D structure. Meanwhile, it can also effectively shorten the migration path of lithium ions, and make up for the deficiency of the low lithium ion diffusion rate. Therefore, the dynamics properties of the electrode materials could be enhanced.

Abstract:Ti-doped Fe2O3 photoanode was obtained through metal–organic decomposition method. The physical and photophysical properties of the hematite photoanode were investigated by X-ray diffraction (XRD), UV-vis absorption spectroscopy, X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) and the photo-electrochemical performance was evaluated for the Ti-doped Fe2O3 photoanode. In terms of maximizing the photoelectrochemical performances of the Ti-doped Fe2O3 photoanodes, the doping concentration of titanium was optimized. The Ti-doped Fe2O3 photoanode exhibits improved photoelectrochemical performance after the electrochemical surface pretreatment. The photoelctrochemical response of hematite photoanode can be improved by both titanium doping and the electrochemical surface pretreatment. Based on the analysis of the Mott–Schottky plots and electrochemical impedance spectra (EIS), a possible mechanism was proposed to explain the reason for the enhancement of photocurrent.

Abstract:Changes in concentrations of oxidative material, antioxidase activities and chlorophyll fluorescence were investigated in Potamogeton polygonifolius exposed to different concentrations of ammonium nitrogen. The results show that 10mg/L of ammonium nitrogen had a little effect on photosynthetic capacity of P. polygonifolius. However, the 5 mg/L to 10 mg/L concentration of ammonium nitrogen could increase oxygen radicals and enhance the defensive capacity by stimulating the antioxidant enzymes activity and increasing content of secondary metabolites. 10 mg/L concentration of ammonium nitrogen had significant effect on the activity of antioxidant enzymes and content of secondary metabolites. The increased antioxidant capacity may alleviate ammonium induced oxidative stress, and thus enhance the endurance of plants to cope with ammonium stress. Overall, higher concentration of ammonium nitrogen had some effect on P. polygonifolius and consequently, the concentration and impact of ammonium nitrogen should be considered when using P. polygonifolius was chosen as candidate plants for the to remediate water ecosystem.

Abstract:This study utilized the MTT assay to detect the effect of Veronica ciliata Fisch. ethyl acetate extract (VEAE) on the proliferation of different cancer cells (A549, Hela, U20S, MCF-7, SMMC-7721) and select the most sensitive cells. Furthermore, the mechanism of VEAE inhibiting cancer cells proliferation was measured by DAPI staining, Annexin-V/PI staining and quantitative real-time PCR. MTT assay showed that the proliferation of five cancer cells were gradually suppressed with the increasing of concentration and treatment time of VEAE. And VEAE exhibited the strongest inhibitory effect on MCF-7 cells, and IC50 of VEAE reached to minimum as 63.42±0.19 μg/mL. Further studies by DAPI staining and Annexin-V/PI staining showed that after treatment of MCF-7 cells with VEAE, cell shrinkage and turn round, the ratios of apoptotic cells increased from 5.00% (control group) to 47.45% with the increasing of concentration of VEAE. Quantitative real-time PCR showed that VEAE could promote the expression of Caspase-3, Caspase-9 , Bax genes and inhibit the expression of Bcl-2 gene. It indicated that VEAE could inhibit cells proliferation and induce cells apoptosis. The mechanism may be associated with the expression of apoptosis related genes.

Abstract:The antibody microarray technique was used to detect the expression of 20 kinds of helper T cellassociated inflammatory cytokines in serum of 53 patients suffered with autoimmune liver disease (AILD). Combining with the clinical biochemical data of liver function to analyze the expression characteristics and differences in inflammatory factors in serum of patients with autoimmune liver disease (AILD). The results showed that the levels of IL4 and TGFβ1 in serum of patients with AIH-PBC OS were significantly higher than those of PBC (P<0.05), while the levels of IL-4 in serum of patients with AIH-PBC OS were significantly higher than that of healthy controls (P<0.05). The levels of IL-4 and TGFβ1 in serum of PBC patients were significantly lower than those of healthy controls (P<0.05).The level of TGFβ1 in serum of PBC patients was negatively correlated with ALT (r=-0.6301, P=0.0135) and AST (r=-0.7443, P=0.0030). Conclusion: the expression levels of IL-4 and TGFβ1 in the blood serum of AIH-PBC OS, PBC patients and the expression level of TGFβ1 was of favorable correlation with the liver function indexes of AILD patients，which indicates it is potential application in AILD screening, diagnosis, and prognosis.

Abstract:The Gastrodia elata polysaccharides were purified using a macroporous adsorption resins method. By comparing the Gastrodia elata polysaccharides separation effect of eight different types （AB-8、D101、LX-17、D301、NKA-9、S-8、LSD-001、ADS-7）of macroporous resin, D101 was selected as the ideal adsorbent as it had a strong adsorption ability and a high desorption rate. The optimal purification technology was as follows: loading rate1 BV/h, loading concentration 4 mg/mL, 60% ethanol as suitable elution solvent from the resin, the elution solvent volume 3 BV and the elution flow rate 2 BV/h. The purity of Gastrodia elata polysaccharide was increased from 15.6% to 65.7%, which indicated that macroporous resin D101 had better purification effect on Gastrodia elata polysaccharide.

Abstract:In order to observe the combined utilization effect of metformin and Salvia miltiorrhiza bge. f. alba on diabetes mellitus type 2, MTT method, glycemic and insulintest, hematoxylin eosin (HE) staining and immunohistochemical staining were carried out in this paper. MTT test results show that combined utilization of metformin and Salvia miltiorrhiza bge. f. albacan inhibit the apoptosis of INS-1 cells. In the treatment of diabetic rats, combined utilization appears to effectively control to blood sugar. HE staining and immunohistochemical staining results show that Salvia miltiorrhiza bge.f. alba can promote the production of Bcl-2 proteins, weaken the ability of Bax proteins to induce apoptosis, in the mean time, metformin has the effect on increasing blood sugar uptake and utilization, ultimately achieve glycemic control purposes. Combined utilization of metformin and Salvia miltiorrhiza bge. f. alba has the potential to be an effective method to the treatment of diabetes.

Abstract:The study area was located in the Huanghuaidian sub-basin of Aohanqi, Inner Mongolia, and 5 clusters of samples were selected in the ten-year-old Caragana korshinskii plantation, on the slope and the slope.The roots were collected by a quarter circle method, and the standard plexus root system was divided into fine root, middle root and bone root.The length and the content of free amino acid were measured.By comparing the differences in the length of each root of the different soil moisture content, the content of free amino acids in the roots of the two species was compared and analyzed.The trend of free amino acid and free proline in different soil water content and the trend of free amino acid average content and root length were obtained.The results show: (1) The length and free proline content of the major organs were negatively correlated with soil water content.(2) There was a positive correlation between the free proline content and the root system.(3) The correlation coefficients of free amino acid content between the two groups were between 0.980 and 0.997, and the correlation was significant.(4) There was a positive correlation between the average content of free proline and the specific surface area of fine roots and R2=0.9371.It is proved that free proline plays an important role in plant resistance to drought stress and provides scientific basis for vegetation restoration of Caragana korshinskii and the interlaced zone of agriculture and grazing in Inner Mongolia.

Abstract:In this experiment, the MCR1 gene enzyme catalytic domain derived from E.coli was cloned and expressed in E.coli expression system. Purified proteins with high purity and good homogeneity were obtained by affinity chromatography, anion exchange chromatography and molecular sieve chromatography. The protein crystals of the enzyme catalyzed region were screened by the method of seating drop and the hanging drop. After collecting x-ray data, the structure of enzyme catalytic region was analyzed by molecular displacement method, and the resolution reached 1.63 angstrom. Four zinc ion signals were detected by the anomalous scattering signal. The structural analysis found that zinc ions was closely related to the surrounding amino acids of Thr285, His465, His466 and His395 , and Thr285 was phosphorylated. After the mutation of Thr285, His465, His466 and His395 to alanine, the resistance of host bacteria to colistin decreased significantly, indicating that the region was closely related to enzyme activity. In this experiment, the structure of MCR1 enzywas analyzed, me active region and the active center of enzyme was identified, which provided useful information for searching for anti MCR1 targeted drugs.