Abstract:The dry roots of Angelica decursiva and Peucedanum praeruptorum are used as Chinese traditional medicine for a long time. This study applied MaxEnt (Maximun Entropy) ecological niche modeling to predict the potential range of Qianhu and Zihuaqianhu in China on the basis of occurrence points. The results indicated that: environmental factors such as Mean temperature of the coldest quarter, Monthly mean diurnal temperature range, Min temperature of the coldest month, Precipitation of the driest month, and Precipitation of the driest quarter are greatly influenced the size of Qianhu's and Zihuaqianhu's potential range. Potential distribution areas of two plants are more widely than the realistic distribution areas. Some mountain areas of Qinling Mountains, Nanling and Zhejiang province are the most suitable area (adaptive index >0.71). The difference of distribution in Taiwan, Gansu, Xizang province can provide the basis for the discrimination. With the wild resource reducing and demands increasing, cultivation of plant in the most suitable area is feasible way to increase output of production and protection of wild resources diversity of Chinese medicinal materials.